BIOLOGICAL TARGETS Inc. has products and technologies in the following areas:

• Molecular Targets for Insecticide Development - BTI has addressed the need for new targets by developing unique approaches for target identification and screening of insecticidal compounds. The Company has developed a proprietary technology application platform, SPADE™ and DELVE™, to construct customized gene libraries, InsectaCLONE™, and insect cell-based protein expression panels, InsectOME™, that can be readily utilized to screen potential insecticide targets, thereby reducing the time and expense associated with insecticide development. BTI has built a mosquito-specific potential target set, MosquitOME™ that can be used for simultaneous screening of multiple proteins for rapid identification and validation of new insecticides against mosquitoes. BTI also has identified potential receptors for Bt insecticidal proteins, which will enable the design of insecticidal proteins and new plant insecticidal traits as well as provide for screening of insecticidal agents.

• Bt-based Biopesticides - BTI has three new strains of Bt, which can be used to control a variety of pest insects. One of the strains kills a wide range of pests in three orders of insects: Lepidoptera (moths), Coleoptera (beetles) and Diptera (mosquitoes and black flies) as well as various nematodes. A second strain is highly efficient against three major mosquito vectors, Culex pipiens, Aedes aegypti and Anopheles gambiae, which transmit human and animal pathogens that are responsible for causing protozoan diseases such as malaria, filarial diseases such as heartworm and viral diseases such as yellow fever, dengue fever and encephalitis. BTI’s mosquitocidal Bt strain is dramatically more potent and much faster acting than any other strain of Bt currently used in commercial vector control products. The third strain, isolated in Texas,
kills the red imported fire ant.

• Environmental Technology Products - Improving soil stability, enhancing water and nutrient retention and increasing its fertility are important in agricultural, farming, land development and erosion control practices. BTI owns a unique, biologically-based, non-corrosive soil improvement and soil-stabilization agent, RECLAFIL™, which is useful for increasing soil water and nutrient retention and controlling erosion. RECLAFIL™ is certified 100% organic by the Organic Materials Review Institute (OMRI). When introduced to a soil system, RECLAFIL™ provides a biologically sustainable environment because it dramatically increases the volume of water retained by soil (up to 500%). RECLAFIL™ improves soil structure and enriches its organic matrix without any adverse environmental effects. The market potential for RECLAFIL™ is immensely high since it has broad applications in agricultural and industrial practices including organic farming, vegetation and turf improvement, land development, road construction, land reclamation, bioremediation and erosion control.

• Bioinformatics Service - BTI has a highly trained and experienced professional scientific staff that is capable of applying the power of computational biology to build solutions to complex biological and data analysis problems faced by scientists in public and private research institutes, biotechnology companies, and universities. BTI supports the entire spectrum from hands-on partnering to outsourcing entire projects.